Exponent has expertise in finite element (FE) analysis of biomaterials and medical devices using state-of-the-art modeling and analysis software (ABAQUS®, HyperWorks®, LS-DYNA®). We specialize in developing and using detailed, validated computational models to evaluate devices for design evaluations, patent litigation, product liability, or regulatory submissions. We help our clients solve a variety of challenges associated with device design, design optimization, and interaction with bone and soft tissues.
In addition to our project experience in assessing various aspects of medical devices using FE analysis, Exponent has many years of industry and research experience in FE modeling of orthopaedic, spine, vascular, and tissue implants, as well as biomaterial modeling.
Orthopaedic Implants 
Exponent uses FE models of various joints for evaluating surgical procedures and clinical performance.
- Subject-specific anatomy based on medical imaging
- Non-homogeneous bone moduli based on bone mineral density (via calibrated CT)
- Robust contact algorithms for implant and bone interactions
- Customized implant geometries
- Virtual experiments to simulate implantation of devices
- Parametric analysis to account for variations in design, surgical, and patient factors
Spine Implants 
Exponent conducts FE spine modeling to evaluate in situ stress states of implantable devices and surrounding biological structures. Results from these analyses, combined with data from our retrieval collection, provide valuable insight into performance and potential failure modes for spine implant devices.
- Subject-specific anatomy based on medical imaging
- Non-homogeneous bone moduli based on bone mineral density (via calibrated CT)
- Robust contact algorithms for implant and facet interactions
- Analysis of total disc replacement impingement mechanics
- Evaluation of implant functionality
Vascular and Tissue Implants 
Exponent uses FE models of various vascular and tissue implants for evaluating design, manufacturing, and delivery procedures, along with clinical performance.
Biomaterial Modeling 
Exponent uses FE models of various biomaterials (processing, sterilization) to capture the multiaxial failure behavior.
- Derived user-defined material models for application in ABAQUS® and LS-DYNA® platforms
- Validated against experimental data using ASTM protocols
- Incorporated into implant FE models to evaluate wear potential and fracture risk for various biomaterial formulations
- Allows for effective evaluation of loading, design, and surgical variations
- Serves as a surrogate for simulator studies